CATH Classification

Domain Context

CATH Clusters

Superfamily Adenosylhomocysteinase-like
Functional Family Adenosylhomocysteinase

Enzyme Information

3.3.1.1
Adenosylhomocysteinase.
based on mapping to UniProt A0A087WNH6
S-adenosyl-L-homocysteine + H(2)O = L-homocysteine + adenosine.
-!- The NAD(+) cofactor appears to bring about a transient oxidation at C-3' of the 5'-deoxyadenosine residue, thus labilizing the thioether bond cf. EC 5.5.1.4.

UniProtKB Entries (1)

A0A087WNH6
SAHH_BRAEL
Bradyrhizobium elkanii
Adenosylhomocysteinase

PDB Structure

PDB 5M66
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii.
Manszewski, T., Szpotkowski, K., Jaskolski, M.
IUCrJ