CATH Classification

Domain Context

CATH Clusters

Superfamily 1.50.10.10
Functional Family alpha-1,2-Mannosidase

Enzyme Information

3.2.1.113
Mannosyl-oligosaccharide 1,2-alpha-mannosidase.
based on mapping to UniProt Q9UKM7
Hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man(9)(GlcNAc)(2).
-!- Involved in the synthesis of glycoproteins.

UniProtKB Entries (1)

Q9UKM7
MA1B1_HUMAN
Homo sapiens
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

PDB Structure

PDB 5KK7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway.
Xiang, Y., Karaveg, K., Moremen, K.W.
Proc. Natl. Acad. Sci. U.S.A.