CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.640 | Aspartate Aminotransferase; domain 2 |
|
3.40.640.10 | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
Domain Context
CATH Clusters
| Superfamily | Type I PLP-dependent aspartate aminotransferase-like (Major domain) |
| Functional Family | 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase |
Enzyme Information
| 2.6.1.109 |
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase.
based on mapping to UniProt Q8EEB1
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate + 2-oxoglutarate = 8-dehydro-3-deoxy-alpha-D-manno-octulosonate + L-glutamate.
-!- The enzyme, characterized from the bacterium Shewanella oneidensis, forms 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. -!- Cf. EC 1.1.3.48.
|
UniProtKB Entries (1)
| Q8EEB1 |
KDNA_SHEON
Shewanella oneidensis MR-1
8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase
|
PDB Structure
| PDB | 5K8B |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of KdnB and KdnA from Shewanella oneidensis: Key Enzymes in the Formation of 8-Amino-3,8-Dideoxy-d-Manno-Octulosonic Acid.
Biochemistry
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