CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.1820 | alpha/beta hydrolase |
Domain Context
CATH Clusters
| Superfamily | alpha/beta hydrolase |
| Functional Family | putative methylesterase 11, chloroplastic |
Enzyme Information
| 3.1.1.82 |
Pheophorbidase.
based on mapping to UniProt O23512
Pheophorbide a + H(2)O = pyropheophorbide a + methanol + CO(2).
-!- Forms part of the chlorophyll degradation pathway, and is found in higher plants and in algae. -!- In higher plants it participates in de-greening processes such as fruit ripening, leaf senescence, and flowering. -!- Exists in two forms: type 1 is induced by senescence whereas type 2 is constitutively expressed. -!- Highly specific for pheophorbide as substrate (with a preference for pheophorbide a over pheophorbide b) as other chlorophyll derivatives such as protochlorophyllide a, pheophytin a and c, chlorophyll a and b, and chlorophyllide a cannot act as substrates. -!- Another enzyme, called pheophorbide demethoxycarbonylase (PDC), produces pyropheophorbide a from pheophorbide a without forming an intermediate although the precise reaction is not yet known.
|
UniProtKB Entries (1)
| O23512 |
PPD_ARATH
Arabidopsis thaliana
Probable pheophorbidase
|
PDB Structure
| PDB | 5HK8 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal strucutre of a methylesterase protein MES16 from Arabidopsis
Biochem.Biophys.Res.Commun.
|
