CATH Domain 5efxA00

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	Rho guanine nucleotide exchange factor 2

Enzyme Information

UniProtKB Entries (1)

ARHG2_HUMAN

Homo sapiens

Rho guanine nucleotide exchange factor 2

PDB Structure

PDB	5EFX
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of hGEF-H1 PH domain provides insight into incapability in phosphoinositide binding Jiang, Y., Jiang, H., Zhou, S., Meng, B., Liu, Z.J., Ouyang, S. Biochem.Biophys.Res.Commun.