CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.210 | Beta Polymerase; domain 3 | |
3.30.210.10 | DNA polymerase, thumb domain |
Domain Context
CATH Clusters
Superfamily | DNA polymerase, thumb domain |
Functional Family | DNA polymerase lambda |
Enzyme Information
4.2.99.- |
Other carbon-oxygen lyases.
based on mapping to UniProt Q9UGP5
|
2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt Q9UGP5
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
Q9UGP5 |
DPOLL_HUMAN
Homo sapiens
DNA polymerase lambda
|
PDB Structure
PDB | 5DDY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural Mechanism for the Fidelity Modulation of DNA Polymerase lambda
J.Am.Chem.Soc.
|