CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.10 | Thrombin, subunit H |
|
2.40.10.10 | Trypsin-like serine proteases |
Domain Context
CATH Clusters
| Superfamily | Trypsin-like serine proteases |
| Functional Family | Anionic trypsin-2 |
Enzyme Information
| 3.4.21.4 |
Trypsin.
based on mapping to UniProt P35030
Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.
-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.
|
UniProtKB Entries (1)
| P05067 |
A4_HUMAN
Homo sapiens
Amyloid-beta precursor protein
|
PDB Structure
| PDB | 5C67 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Combinatorial protein engineering of proteolytically resistant mesotrypsin inhibitors as candidates for cancer therapy.
Biochem.J.
|