CATH Classification
Level | CATH Code | Description |
---|---|---|
1 | Mainly Alpha | |
1.10 | Orthogonal Bundle | |
1.10.510 | Transferase(Phosphotransferase); domain 1 | |
1.10.510.10 | Transferase(Phosphotransferase) domain 1 |
Domain Context
CATH Clusters
Superfamily | Transferase(Phosphotransferase) domain 1 |
Functional Family | dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1 |
Enzyme Information
2.7.12.1 |
Dual-specificity kinase.
based on mapping to UniProt Q13627
ATP + a protein = ADP + a phosphoprotein.
-!- This family of enzymes can phosphorylate both Ser/Thr and Tyr residues. -!- Formerly EC 2.7.1.37.
|
UniProtKB Entries (1)
Q13627 |
DYR1A_HUMAN
Homo sapiens
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
|
PDB Structure
PDB | 5A3X |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Probing the ATP-Binding Pocket of Protein Kinase Dyrk1A with Benzothiazole Fragment Molecules
J.Med.Chem.
|