CATH Classification

Domain Context

CATH Clusters

Superfamily Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
Functional Family Malate dehydrogenase

Enzyme Information

1.1.1.37
Malate dehydrogenase.
based on mapping to UniProt P40926
(S)-malate + NAD(+) = oxaloacetate + NADH.
-!- Also oxidizes some other 2-hydroxydicarboxylic acids.

UniProtKB Entries (1)

P40926
MDHM_HUMAN
Homo sapiens
Malate dehydrogenase, mitochondrial

PDB Structure

PDB 4WLV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of NAD bound MDH2
Eo, Y.M., Han, B.G., Ahn, H.C.
To Be Published