CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.710 | Potassium Channel Kv1.1; Chain A | |
3.30.710.10 | Potassium Channel Kv1.1; Chain A |
Domain Context
CATH Clusters
Superfamily | Potassium Channel Kv1.1; Chain A |
Functional Family | Transcription elongation factor |
Enzyme Information
UniProtKB Entries (1)
P40337 |
VHL_HUMAN
Homo sapiens
Von Hippel-Lindau disease tumor suppressor
|
PDB Structure
PDB | 4W9L |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure-Guided Design and Optimization of Small Molecules Targeting the Protein-Protein Interaction between the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase and the Hypoxia Inducible Factor (HIF) Alpha Subunit with in Vitro Nanomolar Affinities.
J.Med.Chem.
|