CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase DOB1

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P47047
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P47047
MTR4_YEAST
Saccharomyces cerevisiae S288C
ATP-dependent RNA helicase DOB1

PDB Structure

PDB 4QU4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Mtr4 ratchet helix and arch domain both function to promote RNA unwinding.
Taylor, L.L., Jackson, R.N., Rexhepaj, M., King, A.K., Lott, L.K., van Hoof, A., Johnson, S.J.
Nucleic Acids Res.