CATH Domain 4o3uA01

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Hepatocyte growth factor

Enzyme Information

UniProtKB Entries (1)

MET_HUMAN

Homo sapiens

Hepatocyte growth factor receptor

PDB Structure

PDB	4O3U
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	An allosteric switch for pro-HGF/Met signaling using zymogen activator peptides. Landgraf, K.E., Steffek, M., Quan, C., Tom, J., Yu, C., Santell, L., Maun, H.R., Eigenbrot, C., Lazarus, R.A. Nat.Chem.Biol.