CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.450.60
Functional Family AP complex subunit sigma

Enzyme Information

UniProtKB Entries (2)

P18484
AP2A2_RAT
Rattus norvegicus
AP-2 complex subunit alpha-2
P04601
NEF_HV1H2
HIV-1 M:B_HXB2R
Protein Nef

PDB Structure

PDB 4NEE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4.
Ren, X., Park, S.Y., Bonifacino, J.S., Hurley, J.H.
Elife