CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.40 | Beta Barrel | |
2.40.40 | Barwin-like endoglucanases | |
2.40.40.20 |
Domain Context
CATH Clusters
Superfamily | 2.40.40.20 |
Functional Family | Transitional endoplasmic reticulum ATPase |
Enzyme Information
3.6.4.6 |
Vesicle-fusing ATPase.
based on mapping to UniProt P55072
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.
|
UniProtKB Entries (1)
P55072 |
TERA_HUMAN
Homo sapiens
Transitional endoplasmic reticulum ATPase
|
PDB Structure
PDB | 4KOD |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants.
J.Biol.Chem.
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