CATH Domain 4kkdB03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	mannan-binding lectin serine protease 1 isoform X1

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt P48740

UniProtKB Entries (1)

MASP1_HUMAN

Homo sapiens

Mannan-binding lectin serine protease 1

PDB Structure

PDB	4KKD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) Syndrome. Yongqing, T., Wilmann, P.G., Reeve, S.B., Coetzer, T.H., Smith, A.I., Whisstock, J.C., Pike, R.N., Wijeyewickrema, L.C. J.Biol.Chem.