CATH Domain 4je5D00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.640	Aspartate Aminotransferase; domain 2
	3.40.640.10	Type I PLP-dependent aspartate aminotransferase-like (Major domain)

Domain Context

CATH Clusters

Superfamily	Type I PLP-dependent aspartate aminotransferase-like (Major domain)
Functional Family	Aromatic amino acid aminotransferase

Enzyme Information

2.6.1.57	Aromatic-amino-acid transaminase. based on mapping to UniProt P53090 An aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate. -!- L-methionine can also act as donor, more slowly. -!- Oxaloacetate can act as acceptor. -!- Controlled proteolysis converts the enzyme to EC 2.6.1.1.
2.6.1.39	2-aminoadipate transaminase. based on mapping to UniProt P53090 L-2-aminoadipate + 2-oxoglutarate = 2-oxoadipate + L-glutamate.

UniProtKB Entries (1)

ARO8_YEAST

Saccharomyces cerevisiae S288C

Aromatic/aminoadipate aminotransferase 1

PDB Structure

PDB	4JE5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of Saccharomyces cerevisiae Aro8, a putative alpha-aminoadipate aminotransferase. Bulfer, S.L., Brunzelle, J.S., Trievel, R.C. Protein Sci.