CATH Domain 4hdqA03

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.29	PH-domain like
	2.30.29.30	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Domain Context

CATH Clusters

Superfamily	Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Functional Family	krev interaction trapped protein 1 isoform X1

Enzyme Information

UniProtKB Entries (1)

KRIT1_HUMAN

Homo sapiens

Krev interaction trapped protein 1

PDB Structure

PDB	4HDQ
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Structure of the Ternary Complex of Krev Interaction Trapped 1 (KRIT1) Bound to Both the Rap1 GTPase and the Heart of Glass (HEG1) Cytoplasmic Tail. Gingras, A.R., Puzon-McLaughlin, W., Ginsberg, M.H. J.Biol.Chem.