CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Dynamin-1-like protein isoform 1

Enzyme Information

3.6.5.5
Dynamin GTPase.
based on mapping to UniProt O00429
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.

UniProtKB Entries (1)

O00429
DNM1L_HUMAN
Homo sapiens
Dynamin-1-like protein

PDB Structure

PDB 4H1V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Functional Mapping of Human Dynamin-1-Like GTPase Domain Based on X-ray Structure Analyses.
Wenger, J., Klinglmayr, E., Frohlich, C., Eibl, C., Gimeno, A., Hessenberger, M., Puehringer, S., Daumke, O., Goettig, P.
Plos One