CATH Classification

Domain Context

CATH Clusters

Superfamily DNA Methylase, subunit A, domain 2
Functional Family DNA (cytosine-5)-methyltransferase 1

Enzyme Information

2.1.1.37
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt Q9AXT8
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.

UniProtKB Entries (2)

Q9AXT8
CMT1_MAIZE
Zea mays
DNA (cytosine-5)-methyltransferase 1
P59226
H32_ARATH
Arabidopsis thaliana
Histone H3.2

PDB Structure

PDB 4FT4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Dual Binding of Chromomethylase Domains to H3K9me2-Containing Nucleosomes Directs DNA Methylation in Plants.
Du, J., Zhong, X., Bernatavichute, Y.V., Stroud, H., Feng, S., Caro, E., Vashisht, A.A., Terragni, J., Chin, H.G., Tu, A., Hetzel, J., Wohlschlegel, J.A., Pradhan, S., Patel, D.J., Jacobsen, S.E.
Cell(Cambridge,Mass.)