CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.70.2440
Functional Family

Enzyme Information

2.7.7.6
DNA-directed RNA polymerase.
based on mapping to UniProt Q859P9
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized. -!- See also EC 2.7.7.19 and EC 2.7.7.48.

UniProtKB Entries (1)

Q859P9
RPOLV_BPN4
Escherichia virus N4
Virion DNA-directed RNA polymerase

PDB Structure

PDB 4FF3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Watching the Bacteriophage N4 RNA Polymerase Transcription by Time-dependent Soak-trigger-freeze X-ray Crystallography.
Basu, R.S., Murakami, K.S.
J.Biol.Chem.