CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family

Enzyme Information

1.20.1.1
Phosphonate dehydrogenase.
based on mapping to UniProt O69054
Phosphonate + NAD(+) + H(2)O = phosphate + NADH.
-!- NADP(+) is a poor substitute for NAD(+) in the enzyme from Pseudomonas stutzeri WM88.

UniProtKB Entries (1)

O69054
PTXD_PSEST
Pseudomonas stutzeri
Phosphonate dehydrogenase

PDB Structure

PDB 4E5N
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of phosphite dehydrogenase provide insights into nicotinamide cofactor regeneration.
Zou, Y., Zhang, H., Brunzelle, J.S., Johannes, T.W., Woodyer, R., Hung, J.E., Nair, N., van der Donk, W.A., Zhao, H., Nair, S.K.
Biochemistry