CATH Domain 4dd8D00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.390	Collagenase (Catalytic Domain)
	3.40.390.10	Collagenase (Catalytic Domain)

Domain Context

CATH Clusters

Superfamily	Collagenase (Catalytic Domain)
Functional Family	Disintegrin and metalloproteinase domain-containing protein 22

Enzyme Information

3.4.24.-

Metalloendopeptidases.

based on mapping to UniProt P78325

UniProtKB Entries (1)

ADAM8_HUMAN

Homo sapiens

Disintegrin and metalloproteinase domain-containing protein 8

PDB Structure

PDB	4DD8
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of human ADAM-8 catalytic domain complexed with batimastat. Hall, T., Shieh, H.S., Day, J.E., Caspers, N., Chrencik, J.E., Williams, J.M., Pegg, L.E., Pauley, A.M., Moon, A.F., Krahn, J.M., Fischer, D.H., Kiefer, J.R., Tomasselli, A.G., Zack, M.D. Acta Crystallogr.,Sect.F