CATH Domain 4cvhA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.90	Alpha-Beta Complex
	3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
	3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A

Domain Context

CATH Clusters

Superfamily	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family	D-ribitol-5-phosphate cytidylyltransferase isoform X1

Enzyme Information

2.7.7.40

D-ribitol-5-phosphate cytidylyltransferase.

based on mapping to UniProt A4D126

CTP + D-ribitol 5-phosphate = diphosphate + CDP-ribitol.

UniProtKB Entries (1)

ISPD_HUMAN

Homo sapiens

D-ribitol-5-phosphate cytidylyltransferase

PDB Structure

PDB	4CVH
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Human Ispd is a Cytidyltransferase Required for Dystroglycan O-Mannosylation. Riemersma, M., Froese, D.S., Van Tol, W., Engelke, U.F., Kopec, J., Van Scherpenzeel, M., Ashikov, A., Krojer, T., von Delft, F., Tessari, M., Buczkowska, A., Swiezewska, E., Jae, L.T., Brummelkamp, T.R., Manya, H., Endo, T., Van Bokhoven, H., Yue, W.W., Lefeber, D.J. Chem.Biol.