CATH Domain 4c3zA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	ATP binding cassette subfamily C member 1

Enzyme Information

UniProtKB Entries (1)

MRP1_HUMAN

Homo sapiens

Multidrug resistance-associated protein 1

PDB Structure

PDB	4C3Z
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Nucleotide-Free Crystal Structure of Nucleotide-Binding Domain 1 from Human Abcc1 Supports a 'General-Base Catalysis' Mechanism for ATP Hydrolysis. Chaptal, V., Magnard, S., Gueguen-Chaignon, V., Falson, P., Di Pietro, A., Baubichon-Cortay, H. Biochem.Pharm.