CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase SKI2

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P35207
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P35207
SKI2_YEAST
Saccharomyces cerevisiae S288C
Antiviral helicase SKI2

PDB Structure

PDB 4BUJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Yeast Ski Complex: Crystal Structure and RNA Channeling to the Exosome Complex.
Halbach, F., Reichelt, P., Rode, M., Conti, E.
Cell(Cambridge,Mass.)