1 keywords

CATH Domain 4bcgB01

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.472 Cyclin A; domain 1
Homologous Superfamily 1.10.472.10 Cyclin-like

Domain Context

CATH Clusters

Superfamily Cyclin-like
Functional Family

Enzyme Information

UniProtKB Entries (1)

P50750
CDK9_HUMAN
Homo sapiens
Cyclin-dependent kinase 9

PDB Structure

PDB 4BCG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Substituted 4-(Thiazol-5-Yl)-2-(Phenylamino)Pyrimidines are Highly Active Cdk9 Inhibitors: Synthesis, X-Ray Crystal Structure, Sar and Anti-Cancer Activities.
Shao, H., Shi, S., Huang, S., Hole, A., Abbas, A.Y., Baumli, S., Liu, X., Lam, F., Foley, D.W., Fischer, P.M., Noble, M., Endicott, J.A., Pepper, C., Wang, S.
J.Med.Chem.