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CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease H-like superfamily/Ribonuclease H
Functional Family Poly(A) ribonuclease POP2

Enzyme Information

3.1.13.4
Poly(A)-specific ribonuclease.
based on mapping to UniProt P39008
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.

UniProtKB Entries (1)

P25655
NOT1_YEAST
Saccharomyces cerevisiae S288C
General negative regulator of transcription subunit 1

PDB Structure

PDB 4B8C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Basquin, J., Roudko, V.V., Rode, M., Basquin, C., Seraphin, B., Conti, E.
Mol.Cell
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