CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.140 | 8 Propeller | |
2.140.10 | Methanol Dehydrogenase; Chain A | |
2.140.10.30 | Dipeptidylpeptidase IV, N-terminal domain |
Domain Context
CATH Clusters
Superfamily | Dipeptidylpeptidase IV, N-terminal domain |
Functional Family | Dipeptidyl peptidase 4 |
Enzyme Information
3.4.14.5 |
Dipeptidyl-peptidase IV.
based on mapping to UniProt P27487
Release of an N-terminal dipeptide, Xaa-Yaa-|-Zaa-, from a polypeptide, preferentially when Yaa is Pro, provided Zaa is neither Pro nor hydroxyproline.
-!- A membrane-bound serine-type peptidase in mammals. -!- EC 3.4.14.11 catalyzes a similar reaction. -!- Belongs to peptidase family S9B.
|
UniProtKB Entries (1)
P27487 |
DPP4_HUMAN
Homo sapiens
Dipeptidyl peptidase 4
|
PDB Structure
PDB | 3W2T |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site
Biochem.Biophys.Res.Commun.
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