CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family Geranyl diphosphate 2-C-methyltransferase

Enzyme Information

2.1.1.255
Geranyl diphosphate 2-C-methyltransferase.
based on mapping to UniProt Q9F1Y5
S-adenosyl-L-methionine + geranyl diphosphate = S-adenosyl-L-homocysteine + (E)-2-methylgeranyl diphosphate.
-!- This enzyme, along with EC 4.2.3.118, produces 2-methylisoborneol, an odiferous compound produced by soil microorganisms with a strong earthy/musty odor. -!- Formerly EC 2.1.1.n6.

UniProtKB Entries (1)

Q9F1Y5
GPPMT_STRCO
Streptomyces coelicolor A3(2)
Geranyl diphosphate 2-C-methyltransferase

PDB Structure

PDB 3VC2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of Geranyl Diphosphate C-Methyltransferase from Streptomyces coelicolor and Implications for the Mechanism of Isoprenoid Modification.
Koksal, M., Chou, W.K., Cane, D.E., Christianson, D.W.
Biochemistry