CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family Enoyl-[acyl-carrier-protein] reductase [NADH]

Enzyme Information

UniProtKB Entries (1)

Q5NGQ3
Q5NGQ3_FRATT
Francisella tularensis subsp. tularensis SCHU S4
Enoyl-[acyl-carrier-protein] reductase [NADH]

PDB Structure

PDB 3UIC
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and enzymatic analyses reveal the binding mode of a novel series of Francisella tularensis enoyl reductase (FabI) inhibitors.
Mehboob, S., Hevener, K.E., Truong, K., Boci, T., Santarsiero, B.D., Johnson, M.E.
J.Med.Chem.