CATH Domain 3rm5B02

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.910	Heme Oxygenase; Chain A
	1.20.910.10	Heme oxygenase-like

Domain Context

CATH Clusters

Superfamily	Heme oxygenase-like
Functional Family	Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

Enzyme Information

2.7.4.7	Phosphooxymethylpyrimidine kinase. based on mapping to UniProt Q08224 ATP + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine = ADP + 4-amino-2- methyl-5-(diphosphooxymethyl)pyrimidine.
2.7.1.49	Hydroxymethylpyrimidine kinase. based on mapping to UniProt Q08224 ATP + 4-amino-5-hydroxymethyl-2-methylpyrimidine = ADP + 4-amino-2- methyl-5-(phosphomethyl)pyrimidine. -!- CTP, UTP and GTP can act as donors.

UniProtKB Entries (1)

THI20_YEAST

Saccharomyces cerevisiae S288C

Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

PDB Structure

PDB	3RM5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of trifunctional THI20 from yeast. French, J.B., Begley, T.P., Ealick, S.E. Acta Crystallogr.,Sect.D