CATH Classification

Domain Context

CATH Clusters

Superfamily 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Functional Family 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Enzyme Information

4.6.1.12
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.
based on mapping to UniProt Q5NFU1
2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.
-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

Q5NFU1
ISPF_FRATT
Francisella tularensis subsp. tularensis SCHU S4
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

PDB Structure

PDB 3RE3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of 2-C-Methyl-D-Erythritol 2,4-Cyclodiphosphate Synthase from Francisella tularensis
Kim, Y., Makowska-Grzyska, M., Kwon, K., Anderson, W.F., Joachimiak, A., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published