CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family ATP-dependent RNA helicase SUPV3L1, mitochondrial

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt Q8IYB8
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

Q8IYB8
SUV3_HUMAN
Homo sapiens
ATP-dependent RNA helicase SUPV3L1, mitochondrial

PDB Structure

PDB 3RC8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human Suv3 protein reveals unique features among SF2 helicases.
Jedrzejczak, R., Wang, J., Dauter, M., Szczesny, R.J., Stepien, P.P., Dauter, Z.
Acta Crystallogr.,Sect.D