CATH Classification

Domain Context

CATH Clusters

Superfamily PK beta-barrel domain-like
Functional Family Pyruvate kinase

Enzyme Information

2.7.1.40
Pyruvate kinase.
based on mapping to UniProt Q8ZYE0
ATP + pyruvate = ADP + phosphoenolpyruvate.
-!- UTP, GTP, CTP, ITP and dATP can also act as donors. -!- Also phosphorylates hydroxylamine and fluoride in the presence of CO(2).

UniProtKB Entries (1)

Q8ZYE0
KPYK_PYRAE
Pyrobaculum aerophilum str. IM2
Pyruvate kinase

PDB Structure

PDB 3QTG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of pyruvate kinase from the hyperthermophilic archaeon Pyrobaculum aerophilum: insights into cooperative regulation
Solomons, J.T.G., Johnson, U., Schoenheit, P., Davies, C.
To be Published