CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside Triphosphate Pyrophosphohydrolase
Functional Family Uridine diphosphate glucose pyrophosphatase

Enzyme Information

3.6.1.45
UDP-sugar diphosphatase.
based on mapping to UniProt O95848
UDP-sugar + H(2)O = UMP + alpha-D-aldose 1-phosphate.
-!- UDP-sugar is the best substrate, although other nucleoside-sugar diphosphates are used as substrates with similar Km values but much lower maximum velocities. -!- Thus, this enzyme has a specificity distinct from that of EC 3.6.1.21. -!- Some but not all enzymes of this class also appear to have EC 3.1.3.5 activity.

UniProtKB Entries (1)

O95848
NUD14_HUMAN
Homo sapiens
Uridine diphosphate glucose pyrophosphatase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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