CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.150 | Vaccinia Virus protein VP39 |
Domain Context
CATH Clusters
Superfamily | Vaccinia Virus protein VP39 |
Functional Family | DNA (cytosine-5)-methyltransferase |
Enzyme Information
2.1.1.37 |
DNA (cytosine-5-)-methyltransferase.
based on mapping to UniProt P13864
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
-!- See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/ -!- Formerly EC 2.1.1.73.
|
UniProtKB Entries (1)
P13864 |
DNMT1_MOUSE
Mus musculus
DNA (cytosine-5)-methyltransferase 1
|
PDB Structure
PDB | 3PT9 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.
Science
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