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CATH Classification

Domain Context

CATH Clusters

Superfamily Isochorismatase-like
Functional Family Pyrazinamidase/nicotinamidase PncA

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q50575
3.5.1.19
Nicotinamidase.
based on mapping to UniProt Q50575
Nicotinamide + H(2)O = nicotinate + NH(3).

UniProtKB Entries (1)

Q50575
Q50575_MYCTX
Mycobacterium tuberculosis
Pyrazinamidase

PDB Structure

PDB 3PL1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of the Pyrazinamidase of Mycobacterium tuberculosis: Insights into Natural and Acquired Resistance to Pyrazinamide.
Petrella, S., Gelus-Ziental, N., Maudry, A., Laurans, C., Boudjelloul, R., Sougakoff, W.
Plos One
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