CATH Domain 3nmnD00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.40	Phosphatase 2c; domain 1
	3.60.40.10	PPM-type phosphatase domain

Domain Context

CATH Clusters

Superfamily	PPM-type phosphatase domain
Functional Family	Protein phosphatase 2C 16

Enzyme Information

3.1.3.16

Protein-serine/threonine phosphatase.

based on mapping to UniProt P49597

[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.

-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P49597

P2C56_ARATH

Arabidopsis thaliana

Protein phosphatase 2C 56

PDB Structure

PDB	3NMN
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Identification and mechanism of ABA receptor antagonism. Melcher, K., Xu, Y., Ng, L.M., Zhou, X.E., Soon, F.F., Chinnusamy, V., Suino-Powell, K.M., Kovach, A., Tham, F.S., Cutler, S.R., Li, J., Yong, E.L., Zhu, J.K., Xu, H.E. Nat.Struct.Mol.Biol.

Network disruptions