CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1400
Functional Family Ferrochelatase

Enzyme Information

4.99.1.1
Protoporphyrin ferrochelatase.
based on mapping to UniProt P32396
Protoheme + 2 H(+) = protoporphyrin + Fe(2+).
-!- The enzyme catalyzes the terminal step in the heme biosynthesis pathways of eukaryotes and Gram-negative bacteria.

UniProtKB Entries (1)

P32396
HEMH_BACSU
Bacillus subtilis subsp. subtilis str. 168
Ferrochelatase

PDB Structure

PDB 3M4Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase
Hansson, M.D., Karlberg, T., Soderberg, C.A.G., Sreekanth, R., Warren, M.J., Al-Karadaghi, S., Rigby, S.E.J., Hansson, M.
To be Published