CATH Classification

Domain Context

CATH Clusters

Superfamily Carbon-nitrogen hydrolase
Functional Family

Enzyme Information

3.5.5.1
Nitrilase.
based on mapping to UniProt Q9UYV8
A nitrile + 2 H(2)O = a carboxylate + NH(3).
-!- Acts on a wide range of aromatic nitriles including (indol-3- yl)acetonitrile, and also on some aliphatic nitriles, and on the corresponding acid amides (cf. EC 4.2.1.84).

UniProtKB Entries (1)

Q9UYV8
NITR_PYRAB
Pyrococcus abyssi GE5
Nitrilase

PDB Structure

PDB 3KI8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystallographic analysis of a thermoactive nitrilase.
Raczynska, J.E., Vorgias, C.E., Antranikian, G., Rypniewski, W.
J.Struct.Biol.