CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.710 | Beta-lactamase | |
3.40.710.10 | DD-peptidase/beta-lactamase superfamily |
Domain Context
CATH Clusters
Superfamily | DD-peptidase/beta-lactamase superfamily |
Functional Family | Beta-lactamase |
Enzyme Information
3.5.2.6 |
Beta-lactamase.
based on mapping to UniProt P00811
A beta-lactam + H(2)O = a substituted beta-amino acid.
-!- Zinc is only requires in class-B enzymes. -!- A group of enzymes of varying specificity hydrolyzing beta-lactams; some act more rapidly on penicillins, some more rapidly on cephalosporins. -!- Formerly EC 3.5.2.8.
|
UniProtKB Entries (1)
P00811 |
AMPC_ECOLI
Escherichia coli K-12
Beta-lactamase
|
PDB Structure
PDB | 3IXH |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural bases for stability-function tradeoffs in antibiotic resistance.
J.Mol.Biol.
|