CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.620 | HUPs |
Domain Context
CATH Clusters
| Superfamily | HUPs |
| Functional Family | Pantothenate synthetase |
Enzyme Information
| 6.3.2.1 |
Pantoate--beta-alanine ligase (AMP-forming).
based on mapping to UniProt P9WIL5
ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.
|
UniProtKB Entries (1)
| P9WIL5 |
PANC_MYCTU
Mycobacterium tuberculosis H37Rv
Pantothenate synthetase
|
PDB Structure
| PDB | 3IME |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Application of fragment growing and fragment linking to the discovery of inhibitors of Mycobacterium tuberculosis pantothenate synthetase.
Angew.Chem.Int.Ed.Engl.
|