CATH Classification
Domain Context
CATH Clusters
Superfamily | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
Functional Family | PC4 and SFRS1-interacting protein-like isoform X1 |
Enzyme Information
UniProtKB Entries (2)
P04584 |
POL_HV2RO
Human immunodeficiency virus type 2 (ISOLATE ROD)
Gag-Pol polyprotein
|
O75475 |
PSIP1_HUMAN
Homo sapiens
PC4 and SFRS1-interacting protein
|
PDB Structure
PDB | 3F9K |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75
Plos Pathog.
|