CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family Carboxypeptidase B2

Enzyme Information

3.4.17.20
Carboxypeptidase U.
based on mapping to UniProt Q2KIG3
Release of C-terminal Arg and Lys from a polypeptide.
-!- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U. -!- Activity similar to that of the more stable lysine carboxypeptidase, except no preference is shown for Lys over Arg. -!- Belongs to peptidase family M14.

UniProtKB Entries (1)

Q2KIG3
CBPB2_BOVIN
Bos taurus
Carboxypeptidase B2

PDB Structure

PDB 3DGV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of TAFI provides the structural basis for the intrinsic activity of the proenzyme and short half-life of TAFIa
Anand, K., Pallares, I., Valnickova, Z., Christensen, T., Vendrell, J., Wendt, K.U., Schreuder, H.A., Enghild, J.J., Avil S, F.X.
To be Published