CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.630 | Aminopeptidase | |
3.40.630.10 | Zn peptidases |
Domain Context
CATH Clusters
Superfamily | Zn peptidases |
Functional Family | Carboxypeptidase B2 |
Enzyme Information
3.4.17.20 |
Carboxypeptidase U.
based on mapping to UniProt Q2KIG3
Release of C-terminal Arg and Lys from a polypeptide.
-!- Pro-carboxypeptidase U in plasma is activated by thrombin or plasmin during clotting to form the unstable carboxypeptidase U. -!- Activity similar to that of the more stable lysine carboxypeptidase, except no preference is shown for Lys over Arg. -!- Belongs to peptidase family M14.
|
UniProtKB Entries (1)
Q2KIG3 |
CBPB2_BOVIN
Bos taurus
Carboxypeptidase B2
|
PDB Structure
PDB | 3DGV |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
The crystal structure of TAFI provides the structural basis for the intrinsic activity of the proenzyme and short half-life of TAFIa
To be Published
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