CATH Classification
Level | CATH Code | Description |
---|---|---|
6 | Special | |
6.10 | Helix non-globular | |
6.10.140 | Helix Hairpins | |
6.10.140.1470 |
Domain Context
CATH Clusters
Superfamily | 6.10.140.1470 |
Functional Family |
Enzyme Information
1.14.11.42 |
tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase.
based on mapping to UniProt A2RUC4
7-(3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + 2-oxoglutarate + O(2) = 7-(2-hydroxy-3-amino-3-carboxypropyl)wyosine(37) in tRNA(Phe) + succinate + CO(2).
-!- The enzyme is not active with wybutosine.
|
UniProtKB Entries (1)
A2RUC4 |
TYW5_HUMAN
Homo sapiens
TRNA wybutosine-synthesizing protein 5
|
PDB Structure
PDB | 3AL6 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of a novel JmjC-domain-containing protein, TYW5, involved in tRNA modification.
Nucleic Acids Res.
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