CATH Domain 3aa5X00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.420	Nucleotidyltransferase; domain 5
	3.30.420.10	Ribonuclease H-like superfamily/Ribonuclease H

Domain Context

CATH Clusters

Superfamily	Ribonuclease H-like superfamily/Ribonuclease H
Functional Family	Ribonuclease H

Enzyme Information

3.1.26.4

Ribonuclease H.

based on mapping to UniProt P0A7Y4

Endonucleolytic cleavage to 5'-phosphomonoester.

-!- Acts on RNA-DNA hybrids.

UniProtKB Entries (1)

RNH_ECOLI

Escherichia coli K-12

Ribonuclease HI

PDB Structure

PDB	3AA5
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Protein core adaptability: crystal structures of the cavity-filling variants of Escherichia coli RNase HI Tanaka, M., Chon, H., Angkawidjaja, C., Koga, Y., Takano, K., Kanaya, S. Protein Pept.Lett.