CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.287 | Helix Hairpins |
|
1.10.287.40 | Serine-tRNA synthetase, tRNA binding domain |
Domain Context
CATH Clusters
| Superfamily | Serine-tRNA synthetase, tRNA binding domain |
| Functional Family |
Enzyme Information
| 6.1.1.11 |
Serine--tRNA ligase.
based on mapping to UniProt O58441
(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).
-!- This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1.
|
UniProtKB Entries (1)
| O58441 |
SYS_PYRHO
Pyrococcus horikoshii OT3
Serine--tRNA ligase
|
PDB Structure
| PDB | 2ZR2 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystallographic and mutational studies of seryl-tRNA synthetase from the archaeon Pyrococcus horikoshii.
Rna Biol.
|