CATH Domain 2xs6A00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.555	Phosphatidylinositol 3-kinase; Chain A
	1.10.555.10	Rho GTPase activation protein

Domain Context

CATH Clusters

Superfamily	Rho GTPase activation protein
Functional Family	Phosphatidylinositol 3-kinase regulatory subunit beta

Enzyme Information

UniProtKB Entries (1)

P85B_HUMAN

Homo sapiens

Phosphatidylinositol 3-kinase regulatory subunit beta

PDB Structure

PDB	2XS6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The Structure and Catalytic Mechanism of Human Sphingomyelin Phosphodiesterase Like 3A - an Acid Sphingomyelinase Homolog with a Novel Nucleotide Hydrolase Activity. Lim, S.M., Yeung, K., Tresaugues, L., Ling, T.H., Nordlund, P. FEBS J.