CATH Domain 2xn2A03

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1180	Golgi alpha-mannosidase II

Domain Context

CATH Clusters

Superfamily	Golgi alpha-mannosidase II
Functional Family	Alpha-galactosidase Mel36A

Enzyme Information

3.2.1.22

Alpha-galactosidase.

based on mapping to UniProt G1UB44

Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha- D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.

-!- Also hydrolyzes alpha-D-fucosides.

UniProtKB Entries (1)

G1UB44

MELA_LACAC

Lactobacillus acidophilus NCFM

Alpha-galactosidase Mel36A

PDB Structure

PDB	2XN2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Alpha-Galactosidase from Lactobacillus Acidophilus Ncfm: Insight Into Tetramer Formation and Substrate Binding. Fredslund, F., Abou Hachem, M., Jonsgaard Larsen, R., Gerd Sorensen, P., Coutinho, P.M., Lo Leggio, L., Svensson, B. J.Mol.Biol.