CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family Lysine-specific histone demethylase 1A

Enzyme Information

1.-.-.-
Oxidoreductases.
based on mapping to UniProt O60341

UniProtKB Entries (1)

O60341
KDM1A_HUMAN
Homo sapiens
Lysine-specific histone demethylase 1A

PDB Structure

PDB 2XAG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2.
Binda, C., Valente, S., Romanenghi, M., Pilotto, S., Cirilli, R., Karytinos, A., Ciossani, G., Botrugno, O.A., Forneris, F., Tardugno, M., Edmondson, D.E., Minucci, S., Mattevi, A., Mai, A.
J.Am.Chem.Soc.